Three types of bioinformatic data linked pairwise in a triangle. "Core" RNAs are short sequences appearing abundantly in intersections of sets of deep sequencing reads. Noncoding RNAs (ncRNAs) generally have predicted 2D structures and certain well-formed hairpins of some 20 to 100 nt, possibly with cores embedded in stems. The same ncRNAs can also be associated with proteins in ribonucleoprotein particles (RNPs). Lastly, mRNAs coding the same RNP proteins have 3'UTR regions that might be targeted in an miRNA-like manner by short RNAs, including some core RNAs.
Jeffries et al. BMC Bioinformatics 2010 11:602 doi:10.1186/1471-2105-11-602