Table 3 |
||||||
|
Summary of zebrafish OPEN ZFN target sites, classified by ZiFOpT |
||||||
|
Confidence Score (Active Sites) |
False Positive Rate1 (FPR) |
# of zebrafish transcripts targeted2 |
Average # of ZFN target sites2 in transcripts containing nuclease sites |
# of potential target sites2 eliminated by using ZiFOpT |
||
|
|
||||||
|
** |
** |
25,174 |
(86%) |
4.5 |
0 |
(0%) |
|
> 4 |
24% |
15,565 |
(53%) |
2.3 |
78,934 |
(69%) |
|
> 6 |
14% |
12,622 |
(43%) |
2.0 |
89,580 |
(78%) |
|
> 8 |
7% |
6,942 |
(24%) |
1.5 |
103,877 |
(90%) |
|
|
||||||
|
1estimated from training data 2in coding exons 1-3 **no classification |
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|
Sander et al. BMC Bioinformatics 2010 11:543 doi:10.1186/1471-2105-11-543 |
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