Figure 2.

Performance comparison of five complex detection algorithms. A) F-measure of the five algorithms with their best parameters optimized to two sets of known complexes CYC08 and YHTP08 using the DIP network as input. B) Precision and recall of the methods. Circles, F-measures measured against CYC08 (C) or YHTP08 (Y). Lines, F-measure contours. Two different points on the precision-recall plane can have the same F-measure values if they lie on the same F-measure iso-line. The average F-measure of an algorithm, over the two gold standard sets, is indicated with a star.