Table 16

Relative ranking of affinity scoring schemes for complex detection

PPI network

Wodak

MIPS

Aloy

Method

F1

Norm

F1

Norm

F1

Norm

Total

Norm


MCL

Cons3.19

0.573

1.000

0.407

1.000

0.567

0.970

2.970

1.000

FSW(G+K)

0.541

0.944

0.393

0.965

0.585

1.000

2.909

0.980

ICD(G+K)

0.498

0.871

0.370

0.908

0.543

0.928

2.706

0.911

Boot0.094

0.426

0.744

0.299

0.733

0.400

0.684

2.161

0.728


MCLO

Cons3.19

0.606

1.000

0.471

1.000

0.575

0.939

2.939

1.000

ICD(G+K)

0.533

0.879

0.412

0.875

0.572

0.934

2.688

0.914

FSW(G+K)

0.513

0.847

0.376

0.798

0.612

1.000

2.645

0.900

Boot0.094

0.424

0.700

0.267

0.567

0.392

0.641

1.908

0.649


MCL-CAw

Cons3.19

0.614

1.000

0.487

1.000

0.576

0.921

2.921

1.000

FSW(G+K)

0.576

0.938

0.423

0.868

0.625

1.000

2.806

0.961

ICD(G+K)

0.567

0.923

0.450

0.923

0.578

0.925

2.771

0.949

Boot0.094

0.447

0.728

0.282

0.579

0.416

0.666

1.973

0.675


CMC

Cons3.19

0.604

1.000

0.479

1.000

0.588

1.000

3.000

1.000

Boot0.094

0.577

0.955

0.366

0.764

0.515

0.877

2.597

0.866

ICD(G+K)

0.531

0.880

0.403

0.843

0.480

0.816

2.538

0.846

FSW(G+K)

0.484

0.801

0.338

0.705

0.465

0.791

2.297

0.766


HACO

FSW(G+K)

0.581

1.000

0.396

1.000

0.609

1.000

3.000

1.000

Boot0.094

0.572

0.984

0.380

0.961

0.585

0.961

2.906

0.969

ICD(G+K)

0.565

0.972

0.378

0.956

0.593

0.973

2.902

0.967

Cons3.19

0.495

0.852

0.379

0.957

0.502

0.824

2.634

0.878


Ranking obtained from normalized F1 values.

Srihari et al. BMC Bioinformatics 2010 11:504   doi:10.1186/1471-2105-11-504

Open Data