Comparative clustering of the GvHD dataset. (Left) Identification of non-elliptical shaped populations. (a) SamSPECTRAL could properly identify the red, non-elliptical population, while (b) flowMerge mixed this population with the one below it. (c) FLAME produced satisfactory results in identifying this population. (Right) Identification of low density populations close to dense populations. (d) SamSPECTRAL and (e) flowMerge could identify the low density population shown in red at the centre of the figure correctly, while (f) FLAME merged this population with the other ones surrounding it.
Zare et al. BMC Bioinformatics 2010 11:403 doi:10.1186/1471-2105-11-403