Open Access Highly Accessed Methodology article

HPeak: an HMM-based algorithm for defining read-enriched regions in ChIP-Seq data

Zhaohui S Qin123*, Jianjun Yu34, Jincheng Shen1, Christopher A Maher234, Ming Hu1, Shanker Kalyana-Sundaram34, Jindan Yu5 and Arul M Chinnaiyan234678

Author Affiliations

1 Center for Statistical Genetics, Department of Biostatistics, School of Public Health, University of Michigan, 1415 Washington Heights, Ann Arbor, MI 48109-2029, USA

2 Center for Computational Medicine and Bioinformatics, University of Michigan Medical School, 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218, USA

3 Michigan Center for Translational Pathology, University of Michigan Medical School, 1400 E. Medical Center Drive, Ann Arbor, MI 48109-0940, USA

4 Department of Pathology, University of Michigan Medical School, 1301 Catherine, Ann Arbor, Michigan 48109-0602, USA

5 Division of Hematology/Oncology, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, 676 North St. Clair, Suite 1200, Chicago, IL 60611, USA

6 Comprehensive Cancer Center, University of Michigan Medical School, 1500 E. Medical Center Drive, Ann Arbor, MI 48109-0944, USA

7 Department of Urology, University of Michigan Medical School, 1500 E. Medical Center Drive, Ann Arbor, MI 48109-0330, USA

8 Howard Hughes Medical Institute, 4000 Jones Bridge Road, Chevy Chase, MD 20815-6789, USA

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BMC Bioinformatics 2010, 11:369  doi:10.1186/1471-2105-11-369

Published: 2 July 2010

Additional files

Additional file 1:

More detailed information on methods and additional Tables and Figures.

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