Table 1

Prediction sensitivity (%) of the top three predictions by different geometric approaches and their comparison to IBIS.

Method*

Top1

Top2

Top3


IBIS100

73

89

89

IBIS90

75

91

91

IBIS80

72

88

88

LIGSITEcs

71

79

85

PASS

58

67

75

Q-SiteFinder

52

60

75

SURFNET

42

58

62


*IBIS100, IBIS90, IBIS80 dataset contains unbound query proteins for which the average sequence identity between the unbound protein and members of the binding site clusters containing the bound homolog is no more than 100%, 90% and 80% respectively.

Thangudu et al. BMC Bioinformatics 2010 11:365   doi:10.1186/1471-2105-11-365

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