Figure 6.

Examples of profile estimation. The plot shows four examples of chromosomic profile estimation in samples with SNR = 1.25 (high noise). The version of gBPCR employed was the one which uses () and p_upd = 10^-4. As notations: 1 corresponds to gain, 0 to normal status, -1 to loss. IBD/UPD regions and unspecified LOH regions are depicted with values close to zero. All methods (apart PennCNV) are able to identify the copy-neutral LOH regions, but sometimes dChip divides the biggest lesions in small ones. Only gBPCR and CNAT are able to detect LOH regions due to deletions and in this case CNAT divides the biggest aberrations into small regions of LOH.