Table 2 |
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|
Mean and standard deviation of the (absolute) Student's t statistics to test the null hypothesis of equal means in two flanking PCN regions based on heterozygous SNPs only. |
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|
Heterozygous SNPs only |
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|
|
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|
Signals |
Genotypes |
N/G |
G/L |
N/D |
D/L |
N/N |
|
Raw DH (ρT) |
Birdseed |
7.17 ± 1.13 |
27.79 ± 1.93 |
24.22 ± 1.35 |
8.88 ± 1.04 |
0.78 ± 0.64 |
|
Normalized DH ( |
Birdseed |
21.00 ± 1.45 |
39.42 ± 2.54 |
40.22 ± 2.36 |
11.04 ± 1.13 |
0.74 ± 0.59 |
|
Normalized DH ( |
naive |
18.61 ± 1.39 |
33.38 ± 2.31 |
35.40 ± 2.07 |
9.40 ± 1.01 |
1.06 ± 0.68 |
|
TCN (CT) |
Birdseed |
16.43 ± 1.05 |
18.55 ± 1.26 |
25.69 ± 1.32 |
20.57 ± 1.23 |
2.19 ± 0.99 |
|
|
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|
Greater mean values correspond to greater power to detect a change point. Raw (top line) and TumorBoost-normalized (second and third line) DHs, and TCNs (bottom line). |
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|
Bengtsson et al. BMC Bioinformatics 2010 11:245 doi:10.1186/1471-2105-11-245 |
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