Additional file 1.
Table 1 - Contents of BiGG. BiGG currently contains 7 reconstructions including two versions of E. coli. There are a total of 7234 unique reactions and exchanges in the database. Exchange reactions carry metabolites from the extracellular 'compartment' across the system boundary and are not technically part of the metabolic reconstruction. Translocation reactions carry a metabolite between compartments (possibly performing other transformations). Reactions can be gene associated or not. Every reconstruction contains the 'cytosol' and 'extracellular' compartment. Human and yeast contain 'endoplasmic reticulum', 'mitochondria', 'peroxisome', 'nucleus'. The 'periplasm' in iAF1260, vacuole in yeast, and lysosome in human are unique to these reconstructions.
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Schellenberger et al. BMC Bioinformatics 2010 11:213 doi:10.1186/1471-2105-11-213