|
Resolution: standard / high Figure 9.
Correction of microarray intensity data using models of rank r = 1, 2 and the hybrid rank model NN+GGG for the non-specifically hybridized probes
of the mouse data set. Specific hybridization is corrected using the NN-model in all cases. The figure
shows the averaged intensity as a function of expression as in Fig. 8. The systematic
bias of probes containing the (GGG)1-motif progressively decreases with increasing rank of the model and it virtually
vanishes for the NN+GGG model. Correction using the NNN model provides a plot which
is virtually indistinguishable from that of the NN+GGG model (not shown).
Fasold et al. BMC Bioinformatics 2010 11:207 doi:10.1186/1471-2105-11-207 |