Table 2

Mutation positions for selected oncogenes

Gene

Position (#of mutations)


BRAF(766 aa)

464(1), 466(2), 469(4), 581(1),

596(2), 597(2), 600(60), 601(2)


KRAS(188 aa)

12(99), 13(32), 22(1), 23(1), 61(6),

117(1), 146(10)


CTNNB1 (781 aa)

6(1), 33(3), 34(2), 37(3), 41(2), 45(2)


PIK3CA(1068 aa)

    88
(3), 111(3), 118(1), 124(1), 345(1),

449(1), 453(1), 539(1), 542(5),

545(20), 546(2), 549(1),

    1023
(1),

1025(1), 1047(21), 1049(1), 1066(1)


The number of mutations for each position is shown in parenthesis, positions within clusters from Table 1 are highlighted in bold, and CpG positions are underlined.

Ye et al. BMC Bioinformatics 2010 11:11   doi:10.1186/1471-2105-11-11

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