Table 1

Current classification for chronic renal diseases, and the number of patients in the experimental and control groups

Classification for chronic renal diseases

Exp.

Ctrl.

"Predominant" Inflammatory

IgA Nephropathy (IgAN)

25

6

Systemic lupus erythematosus (SLE)

32

15

"Predominant" Non-Inflammatory

Focal & segmental glomerulosclerosis (FSGS)

10

15

Membranous glomerulonephritis (MGN)

18

15

Minimal change disease (MCD)

4

3

Thin membrane disease (TMD)

6

3

"Predominant" Metabolic

Diabetic nephropathy (DN)

11

3

Total

106

60

The dataset consisted of biopsies from 106 patients diagnosed with one of 7 renal diseases, and compared with biopsies from 60 healthy patients within the same expression analysis batch. A test of significance between the two groups resulted in 747 genes implicated across the 7 chronic renal diseases.

Bhavnani et al. BMC Bioinformatics 2009 10(Suppl 9):S3   doi:10.1186/1471-2105-10-S9-S3