Table 3

PRO annotation coverage by GO terms in release 3.0

Ontology

OBO Relation

# Terms*

Example

GO Molecular Function

has_function

295

PRO:000000650 smad 5 isoform 1 phosphorylated 1

GO:0046332 SMAD binding

NOT has_function

55

PRO:000000478 smad 5 isoform 2

GO:0046332 SMAD binding

GO Cellular Component Complex

part_of

62

PRO:000000178 RING-box protein 2 isoform 1

GO:0000151 ubiquitin ligase complex

NOT part_of

5

PRO:000000179 RING-box protein 2 isoform 2

GO:0000151 ubiquitin ligase complex

GO Cellular Component

located_in

240

PRO:000000457 noggin isoform 1 cleaved 1

GO:0005615 extracellular space

GO Biological Process

participates_in

274

PRO:000000086 chordin isoform 1

GO:0001501 skeletal development

PSI-MOD

has_modification

172

PRO:000000650 smad 2 isoform 1 phosphorylated 1

MOD:00046 O-phospho- L-serine

SO

has_agent

305

TGF-beta receptor type-1 sequence variant 11

SO:1000097 mutation causing amino acid deletion

* Number of PRO terms under the umbrella of the corresponding ontology.

Arighi et al. BMC Bioinformatics 2009 10(Suppl 5):S3   doi:10.1186/1471-2105-10-S5-S3