This article is part of the supplement: Selected Proceedings of the First Summit on Translational Bioinformatics 2008
Ontology driven integration platform for clinical and translational research
The University of Texas Health Science Center at Houston, Houston, Texas, USA
BMC Bioinformatics 2009, 10(Suppl 2):S2 doi:10.1186/1471-2105-10-S2-S2Published: 5 February 2009
Semantic Web technologies offer a promising framework for integration of disparate biomedical data. In this paper we present the semantic information integration platform under development at the Center for Clinical and Translational Sciences (CCTS) at the University of Texas Health Science Center at Houston (UTHSC-H) as part of our Clinical and Translational Science Award (CTSA) program. We utilize the Semantic Web technologies not only for integrating, repurposing and classification of multi-source clinical data, but also to construct a distributed environment for information sharing, and collaboration online. Service Oriented Architecture (SOA) is used to modularize and distribute reusable services in a dynamic and distributed environment. Components of the semantic solution and its overall architecture are described.