Table 10 |
||||||
|
Dispositions of the conventional DC subtypes. |
||||||
|
disposition to circulate in the blood |
disposition to cross-present antigen to CD8+ T cells |
disposition to migrate to the lymph node |
disposition to secrete anti- inflammatory cytokines |
disposition to secrete inflammatory cytokines |
disposition to secrete type 1 interferon |
|
|
|
||||||
|
CD8α-CD11b- DC |
||||||
|
immature |
||||||
|
CD8α-CD11b-DC |
||||||
|
mature |
+ |
|||||
|
CD8α-CD11b-DC |
||||||
|
|
||||||
|
CD8α- CD11b+ DC |
+ |
|||||
|
immature |
+ |
|||||
|
CD8α- CD11b+DC |
||||||
|
mature |
+ |
|||||
|
CD8α- CD11b+DC |
||||||
|
|
||||||
|
CD8α + CD11b-DC |
+ |
+ |
||||
|
immature |
+ |
+ |
||||
|
CD8α + CD11b-DC |
||||||
|
mature |
+ |
+ |
||||
|
CD8α + CD11b-DC |
||||||
|
|
||||||
|
interstitial DC |
||||||
|
immature |
+ |
|||||
|
interstitial DC |
||||||
|
mature |
||||||
|
interstitial DC |
||||||
|
|
||||||
|
Langerhans cell |
||||||
|
CD1a+ |
||||||
|
Langerhans cell |
||||||
|
immature |
+ |
|||||
|
CD1a+ |
||||||
|
Langerhans cell |
||||||
|
mature |
||||||
|
CD1a+ |
||||||
|
Langerhans cell |
||||||
|
CD8αlow |
+ |
+ |
||||
|
Langerhans cell |
||||||
|
immature |
+ |
+ |
||||
|
CD8αlow |
||||||
|
Langerhans cell |
||||||
|
mature |
+ |
+ |
||||
|
CD8αlow |
||||||
|
Langerhans cell |
||||||
|
|
||||||
|
dermal DC |
||||||
|
immature |
+ |
|||||
|
dermal DC |
||||||
|
mature dermal DC |
||||||
|
|
||||||
|
+ indicates the cell type referred to by the row label is related to the disposition referred to by the column heading using the has_disposition relation. |
||||||
|
Masci et al. BMC Bioinformatics 2009 10:70 doi:10.1186/1471-2105-10-70 |
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