BMC Bioinformatics

official impact factor 3.03

Open Access Highly Access Research article

CpG islands or CpG clusters: how to identify functional GC-rich regions in a genome?

Leng Han1,2,3 and Zhongming Zhao2,4*

Author Affiliations

1 State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, PR China

2 Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA 23298, USA

3 Graduate School, Chinese Academy of Sciences, Beijing 100039, PR China

4 Center for the Study of Biological Complexity, Virginia Commonwealth University, Richmond, VA 23284, USA

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BMC Bioinformatics 2009, 10:65 doi:10.1186/1471-2105-10-65

Published: 20 February 2009

Additional files

Additional file 1:

Comparison of the length distribution of CGIs and CGCs. This file includes the comparison of the length distribution of CGIs and CGCs in the human and mouse genomes.

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Additional file 2:

Figure S2. Figure S2 displays the distribution of distance between two neighboring CGCs in the promoter region of human-mouse homologous genes.

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