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Open AccessMethodology article

Bayesian optimal discovery procedure for simultaneous significance testing

Jing Cao1 email, Xian-Jin Xie2 email, Song Zhang2 email, Angelique Whitehurst3 email and Michael A White3 email

1Department of Statistical Science, Southern Methodist University, Dallas, Texas, USA

2Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, Texas, USA

3Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas, USA

author email corresponding author email

BMC Bioinformatics 2009, 10:5doi:10.1186/1471-2105-10-5

Published: 6 January 2009

Additional files

Additional file 1:

Bayesian ODP R code. This file contains the R code to calculate the posterior probability from the Bayesian model and the Bayesian ODP.

Format: TXT Size: 5KB Download file

Additional file 2:

List of selected DE genes under Scenario 1. This file contains the list of the DE genes, along with their true expression status, identified by the different methods from the Golden Spike dataset under Scenario 1 (excluding the 10144 non-spiked-in probsets).

Format: XLS Size: 109KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 3:

List of selected DE genes under Scenario 2. This file contains the list of the DE genes, along with their true expression status, identified by the different methods from the Golden Spike dataset under Scenario 2 (excluding the 2,535 equal fold-change probsets).

Format: XLS Size: 105KB Download file

This file can be viewed with: Microsoft Excel Viewer


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