Bayesian optimal discovery procedure for simultaneous significance testing
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* Corresponding author: Jing Cao jcao@smu.edu
BMC Bioinformatics 2009, 10:5 doi:10.1186/1471-2105-10-5
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Research article
A close examination of double filtering with fold change and t test in microarray analysis Song Zhang, Jing Cao BMC Bioinformatics 2009, 10:402 (8 December 2009) Double filtering using fold change and t test to find differentially expressed genes loses power due to differing assumptions about variance, whereas combining Bayesian mixture models with SAM approaches the performance of the theoretically best likelihood ratio test statistic.
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