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G+C content dominates intrinsic nucleosome occupancy

Desiree Tillo and Timothy R Hughes*

BMC Bioinformatics 2009, 10:442 doi:10.1186/1471-2105-10-442

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BioMed Central: 2 citations

Methodology article   Open Access

A motif-independent metric for DNA sequence specificity

Luca Pinello, Giosuè Lo Bosco, Bret Hanlon, Guo-Cheng Yuan BMC Bioinformatics 2011, 12:408 (21 October 2011)

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Chromatin 'programming' by sequence - is there more to the nucleosome code than %GC?

Amanda Hughes, Oliver J Rando Journal of Biology 2009, 8:96 (23 December 2009)

Abstract | Full text | PDF | PubMed |  Editor’s summary

How far is packaging of DNA by nucleosomes directed by DNA sequence? Hughes and Rando discuss this issue in the light of new research in BMC Bioinformatics indicating that nucleosome occupancy is largely determined by the GC content of DNA.

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