Table 2

Prediction accuracies achieved for each functional site prediction method.

Method

Absolute Recall Rate

Relative Recall Rate

Average Distance between Predicted and Real Centroid (Å)

SitesIdentify

Uniform charge method

47.6%

63.0%

11.2

Conservation method

56.9%

74.7%

9.4

Consurf

58.6%

78.2%

8.2

Crescendo

46.9%

63.8%

10.3

FOD

39.7%

56.1%

10.6

QSiteFinder

40.1%

53.0%

13.0

PDBSiteScan

28.1%

38.4%

15.5

PASS

36.6%

49.3%

14.8

Thematics

35.8%

48.9%

13.5

The absolute and relative recall rates achieved along with the average distance between real and active site centroids for each method.

Bray et al. BMC Bioinformatics 2009 10:379   doi:10.1186/1471-2105-10-379