Methodology article
Regression based predictor for p53 transactivation
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* Corresponding author: Anil G Jegga Anil.Jegga@cchmc.org
1 Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, USA
2 Department of Biomedical Engineering, University of Cincinnati, Cincinnati, USA
3 Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, USA
BMC Bioinformatics 2009, 10:215 doi:10.1186/1471-2105-10-215
Published: 14 July 2009Additional files
Additional file 1:
A list of 199 validated p53 RE acquired from 4 publications with their transactivation prediction by our algorithm and binding affinity prediction by Veprintsev algorithm.
Format: XLS Size: 61KB Download file
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Additional file 2:
A prioritized list of 2026 predicted p53 RE acquired from 3 publications with their prediction score from p53MH and our algorithm.
Format: XLS Size: 512KB Download file
This file can be viewed with: Microsoft Excel Viewer
Additional file 3:
A list of prioritized putative p53 REs that occur in high-confidence putative microRNA promoters based on scores from p53MH and our prediction algorithm are included.
Format: XLS Size: 77KB Download file
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Additional file 4:
A list of p53 REs with 1-fold change in transactivation capacity with varying spacer lengths (Part 1).
Format: TIFF Size: 462KB Download file
Additional file 5:
A list of p53 REs with 1-fold change in transactivation capacity with varying spacer lengths (Part 2).
Format: TIFF Size: 416KB Download file
Additional file 6:
A list of p53 REs with 2-fold change in transactivation capacity with varying spacer lengths.
Format: TIFF Size: 1.2MB Download file
Additional file 7:
A complete list of prioritized SNPs overlapping validated p53 REs with their annotations and predictions through our algorithm.
Format: XLS Size: 36KB Download file
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Additional file 8:
A complete list of inter-species polymorphisms occurring in the validated p53 REs along with their binding predictions through our algorithm.
Format: XLS Size: 246KB Download file
This file can be viewed with: Microsoft Excel Viewer
Additional file 9:
A complete list of thirty-six non-coding SNPs overlapping with a validated p53-RE.
Format: XLS Size: 29KB Download file
This file can be viewed with: Microsoft Excel Viewer