Additional file 3.

A graph with two BIC curves corresponding to the settings with a common λ and cluster-specific λ respectively for the first-stage cluster analysis. Little difference in the BIC values between the two settings is observed. In accordance with the principle of parsimony which favors a simpler model, we opt for the default setting here.

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Lo et al. BMC Bioinformatics 2009 10:145   doi:10.1186/1471-2105-10-145