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Open AccessHighly AccessResearch article

Filtering for increased power for microarray data analysis

Amber J Hackstadt email and Ann M Hess email

Center for Bioinformatics and Department of Statistics, Colorado State University, Fort Collins, CO, 80523, USA

author email corresponding author email

BMC Bioinformatics 2009, 10:11doi:10.1186/1471-2105-10-11

Published: 8 January 2009

Additional files

Additional file 1:

Detailed Statistics on Power from Simulation Study. The table displays the 5th, 25th, 50th, 75th, and 95th quantiles of the observed power for simulation runs. Power was calculated with and without variance filtering for both FDR methods(Benjamini-Hochberg and q-value) using a stated FDR level of 0.05. Both dependent and independent cases were considered over a range of π0 values, where π0 is the proportion of genes which are truly not differentially expressed.

Format: XLS Size: 23KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 2:

Detailed Statistics on FDR from Simulation Study. The table displays the 5th, 25th, 50th, 75th, and 95th quantiles of observed FDR for simulation runs. Observed FDR was calculated with and without variance filtering for both FDR methods (Benjamini-Hochberg and q-value) using a stated FDR level of 0.05. Both dependent and independent cases were considered over a range of π0 values, where π0 is the proportion of genes which are truly not differentially expressed.

Format: XLS Size: 23KB Download file

This file can be viewed with: Microsoft Excel Viewer


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