Metabolic flux balance analysis and the in silico analysis of Escherichia coli K-12 gene deletions

Jeremy S Edwards^1,2 and Bernhard O Palsson¹

¹  Department of Bioengineering, University of California, San Diego La Jolla, CA 92093-0412, USA

²  Harvard Medical School Department of Genetics Warren Alpert Rm. 514 200 Longwood Ave. Boston, MA02115, USA