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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor Tim Sands PhD
Welcome to BMC Bioinformatics published by BioMed Central
BMC Bioinformatics is an open access journal publishing original peer-reviewed research articles in all aspects of the development, testing and novel application of computational and statistical methods for the modeling and analysis of all kinds of biological data, as well as other areas of computational biology.
BMC Bioinformatics (ISSN 1471-2105) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, Thomson Reuters (ISI) and Google Scholar.
Featured articles
BMC Bioinformatics 2009, 10 :S6
Scratchpads, a new social networking tool for natural history researchers and enthusiasts, links information from disparate sources, encourages data sharing, and promotes the ultimate goal of describing and synthesising all facets of the diversity of life.
BMC Bioinformatics 2009, 10 :350
Methods for quantifying cell– cell contact often rely on global descriptors, such as overall cell density, but a new statistical model that accounts for local interactions, such as individual cell-cell distances, reduces noisy data and effectively describes contact inhibition effects.
BMC Bioinformatics 2009, 10 :342
IQuantitator is a sophisticated and novel software package, which uses a statistical inference approach to integrate multiple iTRAQ experiments, allowing users to estimate changes in protein expression levels under various treatment conditions
BMC Bioinformatics 2009, 10 :334
Magellanes is a discovery engine that searches the web for bioinformatics services and organizes them into workflows using a semantic approach.
BMC Bioinformatics 2009, 10 :324
KEGGconverter offers users a single workflow software which merges selected KGML pathway files into a fully functional metabolic network SBML model, enhanced with default kinetics, and ready for simulation purposes.
Volume 10 Suppl 14
Research
Volume 10 Suppl 13
Meeting abstracts
Stockholm, Sweden. 27 June 2009
Volume 10 Suppl 12
Research
Varenna, Italy. 19
more info ]
Research article
A generic algorithm for layout of biological networks Falk Schreiber, Tim Dwyer, Kim Marriott, Michael Wybrow BMC Bioinformatics 2009, 10 :375 (12 [Abstract ] [Provisional PDF ]
Research article
Linguistic feature analysis for protein interaction extraction Timur Fayruzov, Martine De Cock, Chris Cornelis, Veronique Hoste BMC Bioinformatics 2009, 10 :374 (12 [Abstract ] [Provisional PDF ]
Methodology article
A theoretical approach to spot active regions in antimicrobial proteins Marc Torrent, Victoria M Nogues, Ester Boix BMC Bioinformatics 2009, 10 :373 (11 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
Illumina WG-6 BeadChip strips should be normalized separately Wei Shi, Ashish Banerjee, Matthew E Ritchie, Steve Gerondakis, Gordon K Smyth BMC Bioinformatics 2009, 10 :372 (11 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
An empirical Bayesian approach for model-based inference of cellular signaling networks David J Klinke II BMC Bioinformatics 2009, 10 :371 (9 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Elucidation of functional consequences of signalling pathway interactions Adaoha E C Ihekwaba, Phuong T Nguyen, Corrado Priami BMC Bioinformatics 2009, 10 :370 (6 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
RNA folding on the 3D triangular lattice Joel Gillespie, Martin Mayne, Minghui Jiang BMC Bioinformatics 2009, 10 :369 (5 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Database
A biosegmentation benchmark for evaluation of bioimage analysis methods Elisa Drelie Gelasca, Boguslaw Obara, Dmitry Fedorov, Kristian Kvilekval, B. S. Manjunath BMC Bioinformatics 2009, 10 :368 (1 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Database
GLIDERS - A web-based search engine for genome-wide linkage disequilibrium between HapMap SNPs Robert Lawrence, Aaron G Day-Williams, Richard Mott, John Broxholme, Lon R Cardon, Eleftheria Zeggini BMC Bioinformatics 2009, 10 :367 (31 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
(PS)2 -v2: template-based protein structure prediction server Chih-Chieh Chen, Jenn-Kang Hwang, Jinn-Moon Yang BMC Bioinformatics 2009, 10 :366 (31 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Analysis of expressed sequence tags and identification of genes encoding cell-wall-degrading enzymes from the fungivorous nematode Aphelenchus avenae Nurul Karim, John T Jones, Hiroaki Okada, Taisei Kikuchi BMC Genomics 2009, 10 :525 (16 [Abstract ] [Provisional PDF ]
Research
Reactive oxygen and nitrogen species induce protein and DNA modifications driving arthrofibrosis following total knee arthroplasty Theresa A Freeman, Javad Parvizi, Craig J Della Valle, Marla J Steinbeck Fibrogenesis & Tissue Repair 2009, 2 :5 (13 [Abstract ] [Provisional PDF ]
Technical advance
An informatics supported web-based data annotation and query tool to expedite translational research for head and neck malignancies Waqas Amin, Hyunseok P Kang, Ann M Egloff, Harpreet Singh, Kerry Trent, Jennifer Ridge-Hetrick, Raja R Seethala, Jennifer Grandis, Anil V Parwani BMC Cancer 2009, 9 :396 (13 [Abstract ] [Provisional PDF ]
Software
DG-AMMOS: A New tool to generate 3D conformation of small molecules using Distance Geometry and Automated Molecular Mechanics Optimization for in silico Screening. David Lagorce, Tania Pencheva, Bruno O Villoutreix, Maria A Miteva BMC Chemical Biology 2009, 9 :6 (13 [Abstract ] [Provisional PDF ]
Research
Reduced emissions from deforestation and forest degradation (REDD): a climate change mitigation strategy on a critical track Michael Kohl, Thomas Baldauf, Daniel Plugge, Joachim Krug Carbon Balance and Management 2009, 4 :10 (13 [Abstract ] [Provisional PDF ]
Research article
Correlation of microsynteny conservation and disease gene distribution in mammalian genomes Simon C Lovell, Xiting Li, Nimmi R Weerasinghe, Kathryn E Hentges BMC Genomics 2009, 10 :521 (12 [Abstract ] [Provisional PDF ]
Database
The Cytochrome P450 Engineering Database: integration of biochemical properties Demet Sirim, Florian Wagner, Andrey Lisitsa, Juergen Pleiss BMC Biochemistry 2009, 10 :27 (12 [Abstract ] [Provisional PDF ]
Research article
Composite likelihood estimation of demographic parameters Daniel Garrigan BMC Genetics 2009, 10 :72 (12 [Abstract ] [Provisional PDF ]
Research article
The effect of sequencing errors on metagenomic gene prediction Katharina J Hoff BMC Genomics 2009, 10 :520 (12 [Abstract ] [Provisional PDF ]
Review
Computational models in plant-pathogen interactions: the case of Phytophthora infestans
Andres Pinzon, Emiliano Barreto, Adriana Bernal, Luke Achenie, Andres F Gonzalez Barrios, Raul Isea, Silvia Restrepo Theoretical Biology and Medical Modelling 2009, 6 :24 (12 [Abstract ] [Provisional PDF ]
Featured articles 
21 May 2008
