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- Adam Godzik, Sanford-Burnham Medical Research Institute and UCSD
- Lawrence Hunter, University of Colorado Denver
- Igor Jurisica, Ontario Cancer Institute
- Burkhard Morgenstern, University of Gottingen
- Alexey Nesvizhskii, University of Michigan
- Adam Olshen, University of California, San Francisco
- Hanchuan Peng, Howard Hughes Medical Institute
- Graziano Pesole, University of Bari
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- Gordon K Smyth, Walter and Eliza Hall Institute of Medical Research
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Articles
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BMC Bioinformatics 2012, 13:8Integrated analysis of exome sequencing data
The Atlas2 is an analysis suite for variant calling in whole exome sequencing that combines regression models and user-adjustable cutoffs in order to separate true SNPs and INDELs from sequencing and mapping errors, with high sensitivity
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BMC Bioinformatics 2011, 12:480Bias correction for RNA-seq data
The combination of three different strategies for GC-content normalization of RNA-seq data leads to more accurate estimations of gene expression levels and fold-changes, making statistical inference of differential expression less prone to false discoveries.
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BMC Bioinformatics 2011, 12:456Widespread error in biomedical ontologies
Almost a quarter of all existential restrictions in the Open Biomedical Ontologies (OBO) Foundry contain assertions that do not properly describe the underlying biological reality, suggesting that a restriction to fewer, well-defined, relation types is needed.
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BMC Bioinformatics 2011, 12:393Enriching corpora with meta-knowledge
An annotation scheme for meta-knowledge enrichment of biomedical event corpora achieves high levels of inter-annotator agreement when applied to the GENIA event corpus, and facilitates more sophisticated training of information extraction systems.
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BMC Bioinformatics 2011, 12:371Protein complex ontology
ProComp is a component of the Protein Ontology (PRO) database for implementing a logical and consistent representation of protein complexes, and facilitates robust annotation of variations in composition and function contexts within and between species
Hot topic
A semantic web framework to integrate cancer omics data with biological knowledge
BMC Bioinformatics 2012, 13(Suppl 1):S10 (25 January 2012)
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BMC Bioinformatics is an open access, peer-reviewed journal that considers articles on all aspects of the development, testing and novel application of computational and statistical methods for the modeling and analysis of all kinds of biological data, as well as other areas of computational biology.
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Data publishing framework for primary biodiversity data
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UCLA David Geffen School of Medicine, USA
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