Figure 7.

DSN activity against ds and ss RNA. Agarose gel electrophoresis of ds or ss RNA and ds DNA before and after treatment with DSN. Lanes: 1, untreated lambda phage DNA (500 ng) and total RNA (50 ng) from cultured cells; 2, lambda phage DNA and total RNA after incubation with 2 units of DSN for 30 min at 37°C; 3, untreated lambda phage DNA and synthetic ds RNA (2 μg); 4, lambda phage DNA and synthetic ds RNA after incubation with 2 units of DSN for 30 min at 37°C; m, 1-kb ladder (SibEnzyme).