Additional File 4.

Unrooted tree produced by running the alignment in 3 through MrBayes. This tree was rooted by mapping on to the tree of life to produce the tree in figure 3 (see methods). In figure 3 the kangaroo clade has been summarised as one node called 'Kangaroo', and the the two versions of Mouse ARD1 have been replaced by just the Ensembl version. Figure produced using ATV (Zmasek and Eddy, 2001).

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Arnesen et al. BMC Biochemistry 2006 7:13   doi:10.1186/1471-2091-7-13