Table 1

Growth inhibition of different mammalian cell lines by antibiotics

Cell line

Origin

ArcA

ArcB

ApiA

ApiB

BafA1

ConA

IC50 (nM)


L-929

murine connective tissue

0.81a

1.1a

4.5

620

3.2a

0.23a

3Y1

rat, embryogenic fibroblast cell line

0.95

1.1

3.2

310

5.6

1.4

KB-V1b

human cervix carcinoma

48.0

35.0

23.0

1600

7.2

28.0

KB-V1b

(in presence of 11 μM verapamil)

2.3

1.5

7.9

540

4.0

2.7

A-594

human lung carcinoma

0.54

0.69

0.23c

310c

0.4

0.17

M1

mouse, embryogenic fibroblast cell line

0.27

0.35

1.4

190

2.6

0.56


a [17]; b mdr cell line; c [15]

DSMZ: L-929, KB-V1, A-594

3Y1: [33]

M1: [30]

Huss et al. BMC Biochemistry 2005 6:13   doi:10.1186/1471-2091-6-13

Open Data