Inhibition of the V1/Vo holoenzyme activity by the antibiotics. Values represent the means ± S.D. of three independent enzyme preparations. Archazolid A (open circles), archazolid B (solid circles), apicularen A (open triangles) and apicularen B (solid triangles). The specific enzyme activity of the controls without inhibitors was 1.5 ± 0.2 μmol*mg-1 *min-1.
Huss et al. BMC Biochemistry 2005 6:13 doi:10.1186/1471-2091-6-13