Figure 5.

Predicted topologies of H. sapiens PiT2, E. coli PiTA, and A. fulgidus putative phosphate permease. Illustrations of the putative topology of H. sapiens PiT2, E. coli PiTA, and A. fulgidus putative phosphate permease are shown. TM domains were predicted using the TMHMM server (H. sapiens PiT2) and the DAS server (E. coli PiTA and A. fulgidus putative phosphate permease) (Additional File 1 Figure A), see "Methods" for description. The N-terminal and C-terminal PiT-family signature sequences [18] are given in grey letters, and grey stippled lines indicate the predicted placement.