Table 5

Circulating levels of insulin, glucagon, corticosterone and glucose

Male

Female

Significant sex-difference


4 h fasting

Insulin (ng/ml)

2.43 ± 0.45

1.56 ± 0.04

Glucagon (pg/ml)

99.8 ± 6.2

100.9 ± 8.5

Corticosterone (ng/ml)

495.9 ± 9.9

531.5 ± 22.6

Insulin-Glucagon ratio

24.3 ± 4.1

16.0 ± 2.0

P < 0.05

Glucose (mM)

6.7 ± 0.3

6.4 ± 0.2

12 h fasting

Insulin (ng/ml)

3.99 ± 1.75

0.82 ± 0.16

Glucagon (pg/ml)

275.5 ± 122.4

100.9 ± 2.2

Corticosterone (ng/ml)

506.1 ± 20.2

587.4 ± 6.9

P < 0.005

Insulin-Glucagon ratio

16.5 ± 2.3

8.0 ± 1.4

P < 0.05

Glucose (mM)

4.8 ± 0.2

5.2 ± 0.2


Male and female rats were fasted for 4 or 12 h, blood samples were collected and analyzed for insulin, glucagon, corticosterone and glucose. The ratio between insulin and glucagon was calculated. The data are presented as means ± SEM (n = 4) and analyzed using two-way ANOVA and Fisher's LSD test.

Gustavsson et al. BMC Biochemistry 2010 11:38   doi:10.1186/1471-2091-11-38

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