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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor Scott Edmunds, PhD
Welcome to BMC Biochemistry published by BioMed Central
BMC Biochemistry is an open access journal publishing original peer-reviewed research articles in all aspects of biochemical processes, including the structure, function and dynamics of metabolic pathways, supramolecular complexes, enzymes, proteins, nucleic acids and small molecular components of organelles, cells and tissues.
BMC Biochemistry (ISSN 1471-2091) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, Zoological Record, Thomson Reuters (ISI) and Google Scholar.
Featured articles
BMC Biochemistry 2009, 10 :17
Two response regulators of antibacterial peptide production in Lactobacillus plantarum are highly homologous, co-expressed, and bind to the same promoters but differ in their binding affinity and cooperativity, explaining their opposite functions in gene regulation.
BMC Biochemistry 2009, 10 :14
The lipid signaling molecule N-arachidonyl glycine (NAGly) is produced from the endogenous cannabinoid anandamide (AEA) by two pathways - oxidative metabolism of AEA's ethanolamine moiety, and glycine conjugation to arachidonic acid released during AEA hydrolysis by fatty acid amide hydrolase.
BMC Biochemistry 2009, 10 :2
The unwinding of double-stranded DNA in humans as mediated by hRad51, the RecA homolog, is stimulated by the protein hRad52, which possibly acts as a scaffold to bring DNA and hRad51 together.
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Research article
Biochemical characterization of malate synthase G of P. aeruginosa Bart Roucourt, Nikki Minnebo, Patrick Augustijns, Kirsten Hertveldt, Guido Volckaert, Rob Lavigne BMC Biochemistry 2009, 10 :20 (24 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Insights into the role of Val45 and Gln182 of Escherichia coli MutY in DNA substrate binding and specificity Po-Wen Chang, Amrita Madabushi, A-Lien Lu BMC Biochemistry 2009, 10 :19 (12 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Analysis of DNA relaxation and cleavage activities of recombinant Mycobacterium tuberculosis DNA topoisomerase I from a new expression and purification protocol Thirunavukkarasu Annamalai, Neil Dani, Bokun Cheng, Yuk-Ching Tse-Dinh BMC Biochemistry 2009, 10 :18 (11 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
DNA binding kinetics of two response regulators, PlnC and PlnD, from the bacteriocin regulon of Lactobacillus plantarum C11 Daniel Straume, Rune F Johansen, Magnar Bjoras, Ingolf F Nes, Dzung B Diep BMC Biochemistry 2009, 10 :17 (11 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
TIPT2 and geminin interact with basal transcription factors to synergize in transcriptional regulation Mara E Pitulescu, Martin Teichmann, Lingfei Luo, Michael Kessel BMC Biochemistry 2009, 10 :16 (10 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
A novel human NatA Thomas Arnesen, Darina Gromyko, Diane Kagabo, Matthew J Betts, Kristian K Starheim, Jan Erik Varhaug, Dave Anderson, Johan R Lillehaug BMC Biochemistry 2009, 10 :15 (29 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
Research article
The endocannabinoid anandamide is a precursor for the signaling lipid N -arachidonoyl glycine by two distinct pathways Heather B Bradshaw, Neta Rimmerman, Sherry Shu-Jung Hu, Valery M Benton, Jordyn M Stuart, Kim Masuda, Benjamin F Cravatt, David K O'Dell, J Michael Walker BMC Biochemistry 2009, 10 :14 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Biochemical characterization of bovine plasma thrombin-activatable fibrinolysis inhibitor (TAFI) Zuzana Valnickova, Morten Thaysen-Andersen, Peter H BMC Biochemistry 2009, 10 :13 (5 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Exploring the functional interaction between POSH and ALIX and the relevance to HIV-1 release J BMC Biochemistry 2009, 10 :12 (24 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Both Ca2+ and Zn2+ are essential for S100A12 protein oligomerization and function Olga V Moroz, Will Burkitt, Helmut Wittkowski, Wei He, Anatoli Ianoul, Vera Novitskaya, Jingjing Xie, Oxana Polyakova, Igor K Lednev, Alexander Shekhtman, Peter J Derrick, Per Bjoerk, Dirk Foell, Igor B Bronstein BMC Biochemistry 2009, 10 :11 (23 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Conservation of structure and activity in Plasmodium purine nucleoside phosphorylases
Apirat Chaikuad, R. Leo Brady BMC Structural Biology 2009, 9 :42 (3 [Abstract ] [Provisional PDF ]
Research article
Differential expression proteomics to investigate responses and resistance to Orobanche crenata in Medicago truncatula Ma Angeles Castillejo, Ana M. Maldonado, Eliane Dumas-Gaudot, Monica Fernandez-Aparicio, Rafael Susin, Diego Rubiales, Jesus V. Jorrin BMC Genomics 2009, 10 :294 (3 [Abstract ] [Provisional PDF ]
Research
Overexpression of peroxiredoxin I and thioredoxin1 in human breast carcinoma Mee-Kyung Cha, Kyung-Hoon Suh, Il-Han Kim Journal of Experimental & Clinical Cancer Research 2009, 28 :93 (30 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
Simple and efficient site-directed mutagenesis using two single-primer reactions in parallel to generate mutants for protein structure-function studies Oded Edelheit, Aaron Hanukoglu, Israel Hanukoglu BMC Biotechnology 2009, 9 :61 (30 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
The role of YY1 in reduced HP1 alpha gene expression in invasive human breast cancer cells Jason G Lieberthal, Marissa Kaminsky, Christopher N Parkhurst, Naoko Tanese Breast Cancer Research 2009, 11 :R42 (30 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology
Comparison of metal-dependent catalysis by HIV-1 and ASV integrase proteins using a new and rapid, moderate throughput assay for joining activity in solution Mark D. Andrake, Joseph Ramcharan, George Merkel, Xue Zhi Zhao, Terrence R. Burke Jr., Anna Marie Skalka AIDS Research and Therapy 2009, 6 :14 (29 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
A membrane-bound matrix metalloproteinase from Nicotiana tabacum cv. BY-2 is induced by bacterial pathogens Andreas Schiermeyer, Hanna Hartenstein, Manoj K Mandal, Burkhard Otte, Verena Wahner, Stefan Schillberg BMC Plant Biology 2009, 9 :83 (29 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Comparison of two label-free global quantitation methods, APEX and 2D gel electrophoresis, applied to the Shigella dysenteriae proteome Srilatha Kuntumalla, John C Braisted, Shih-Ting Huang, Prashanth P Parmar, David J Clark, Hamid Alami, Quanshun Zhang, Arthur Donohue-Rolfe, Saul Tzipori, Robert D Fleischmann, Scott N Peterson, Rembert Pieper Proteome Science 2009, 7 :22 (29 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Acute heat stress brings down milk secretion in dairy cows by up-regulating the activity of the milk-borne negative feedback regulatory system Nissim Silanikove, Fira Shapiro, Dima Shinder BMC Physiology 2009, 9 :13 (29 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Software
DOTcvpSB, a software toolbox for dynamic optimization in systems biology Tomas Hirmajer, Eva Balsa-Canto, Julio R. Banga BMC Bioinformatics 2009, 10 :199 (29 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Featured articles 
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