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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor Andrea Bucceri
Welcome to BMC Biochemistry published by BioMed Central
BMC Biochemistry is an open access journal publishing original peer-reviewed research articles in all aspects of biochemistry, including metabolic pathways, enzyme functions, and small molecular components of cells and tissues.
BMC Biochemistry (ISSN 1471-2091) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, Zoological Record and Google Scholar.
BMC Biochemistry 2008, 9 :12
In the freeze-tolerant wood frog, Rana sylvatica, long-term viability in frozen muscles requires fine tuning of cellular energetics through modulation of the kinetic parameters and the phosphorylation state of an adenosine deaminase enzyme.
BMC Biochemistry 2008, 9 :8
Putative roles for six proteins in the biosynthesis pathway of pyrroloquinoline quinone, a bacterial redox-active cofactor for numerous alcohol and aldose dehydrogenases, have been assigned in Klebsiella by integrating structural, genomic and functional data.
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Research article
The central proline rich region of POB1/REPS2 plays a regulatory role in epidermal growth factor receptor endocytosis by binding to 14-3-3 and SH3 domain-containing proteins Laura Tomassi, Anna Costantini, Salvatore Corallino, Elena Santonico, Martina Carducci, Gianni Cesareni, Luisa Castagnoli BMC Biochemistry 2008, 9 :21 (22 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Functional and biochemical characterization of the 20S proteasome in a yeast temperature-sensitive mutant, rpt6-1 Aktar Uzzaman Chouduri, Toshinobu Tokumoto, Hideo Dohra, Takashi Ushimaru, Shinpei Yamada BMC Biochemistry 2008, 9 :20 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
Purification and characterization of recombinant human renin for X-ray crystallization studies Zhongren Wu, Maria G Cappiello, Boyd B Scott, Yuri Bukhtiyarov, Gerard M McGeehan BMC Biochemistry 2008, 9 :19 (26 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
Biochemical characterization and cellular imaging of a novel, membrane permeable fluorescent cAMP analog Daniela Moll, Anke Prinz, Cornelia M Brendel, Marco Berrera, Katrin Guske, Manuela Zaccolo, Hans-Gottfried Genieser, Friedrich W Herberg BMC Biochemistry 2008, 9 :18 (25 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Molecular evolution of B6 enzymes: Binding of pyridoxal-5'-phosphate and Lys41Arg substitution turn ribonuclease A into a model B6 protoenzyme Rosa A Vacca, Sergio Giannattasio, Guido Capitani, Ersilia Marra, Philipp Christen BMC Biochemistry 2008, 9 :17 (19 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Modulation of the pharmacological effects of enzymatically-active PLA2 by BTL-2, an isolectin isolated from the Bryothamnion triquetrum red alga Simone CB Oliveira, Fabiana V Fonseca, Edson Antunes, Enilton A Camargo, Rafael P Morganti, Ricardo Apar BMC Biochemistry 2008, 9 :16 (6 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Characterization of Bacillus anthracis arginase: effects of pH, temperature, and cell viability on metal preference Ryan J Viator, Richard F Rest, Ellen Hildebrandt, David J McGee BMC Biochemistry 2008, 9 :15 (3 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Isolation, characterization and molecular cloning of Duplex-Specific Nuclease from the hepatopancreas of the Kamchatka crab Veronika E Anisimova, Denis V Rebrikov, Dmitry A Shagin, Valery B Kozhemyako, Natalia I Menzorova, Dmitry B Staroverov, Rustam Ziganshin, Laura L Vagner, Valery A Rasskazov, Sergey A Lukyanov, Alex S Shcheglov BMC Biochemistry 2008, 9 :14 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
The Mycobacterium tuberculosis Rv2540c DNA sequence encodes a bifunctional chorismate synthase Fernanda Ely, Jos BMC Biochemistry 2008, 9 :13 (29 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Regulation of 5'-adenosine monophosphate deaminase in the freeze tolerant wood frog, Rana sylvatica Christopher A Dieni, Kenneth B Storey BMC Biochemistry 2008, 9 :12 (22 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Hypothesis
An extension of the coevolution theory of the origin of the genetic code Massimo Di Giulio Biology Direct 2008, 3 :37 (5 [Abstract ] [Provisional PDF ]
Short Report
Identification of a non-purple tartrate-resistant acid phosphatase: an evolutionary link to Ser/Thr protein phosphatases? Kieran S Hadler, Thomas Huber, A IAN Cassady, Jane Weber, Jodie Robinson, Allan Burrows, Gregory Kelly, Luke W Guddat, David A Hume, Gerhard Schenk, Jack U Flanagan BMC Research Notes 2008, 1 :78 (4 [Abstract ] [Provisional PDF ]
Database
A Phylogenomic Profile of Hemerythrins, the Nonheme Diiron Binding Respiratory Proteins Xavier Bailly, Stefano Vanin, Christine Chabasse, Kenji Mizuguchi, Serge N Vinogradov BMC Evolutionary Biology 2008, 8 :244 (2 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Heterologous ectoine production in Escherichia coli: by-passing the metabolic bottle-neck Thorsten Bestvater, Petra Louis, Erwin A Galinski Saline Systems 2008, 4 :12 (29 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Review
Conjugated linoleic acid modulation of risk factors associated with atherosclerosis
Yukiko K Nakamura, Nichole Flintoff-Dye, Stanley T Omaye Nutrition & Metabolism 2008, 5 :22 (21 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Diversity in genomic organisation, developmental regulation and distribution of the murine PR72/B" subunits of protein phosphatase 2A Karen Zwaenepoel, Justin V Louis, Jozef Goris, Veerle Janssens BMC Genomics 2008, 9 :393 (20 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research
Critical role for BIM in T cell receptor restimulation-induced death Andrew L Snow, Jo Biology Direct 2008, 3 :34 (20 [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research
Phagocytosis of haemozoin (malarial pigment) enhances metalloproteinase-9 activity in human adherent monocytes: Role of IL-1beta and 15-HETE Mauro Prato, Valentina Gallo, Giuliana Giribaldi, Paolo Arese Malaria Journal 2008, 7 :157 (18 [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Primary research
Alcohol significantly lowers the seizure threshold in mice when co-administered with bupropion hydrochloride Peter H Silverstone, Robert Williams, Louis McMahon, Rosanna Fleming, Siobhan Fogarty Annals of General Psychiatry 2008, 7 :11 (18 [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research article
Uptake of long chain fatty acids is regulated by dynamic interaction of FAT/CD36 with cholesterol/ sphingolipid enriched microdomains (lipid rafts). Robert Ehehalt, Richard Sparla, Thomas Herrmann, Hasan Kulaksiz, Joachim Fullekrug, Wolfgang Stremmel BMC Cell Biology 2008, 9 :45 (13 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
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