Biology for the post-genomic era
Genome Biology publishes research articles, new methods and software tools, in addition to reviews and opinions, from the full spectrum of biology, including molecular, cellular, organism or population biology studied from a genomic perspective, as well as sequence analysis, bioinformatics, proteomics, comparative biology and evolution.
Articles
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Genome Biology 2012, 13:152Host-microbiome interactions
We are what we eat: Mihai Pop highlights our Research article investigating the impact of diet on an infant's gut
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Genome Biology 2012, 13:244Mammalian body size
Peter Visscher and colleagues survey the current known mutations affecting body size in humans, mice, dogs and livestock species
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Genome Biology 2012, 13:R32Infant diet metagenomics
A novel host-microbiome analysis method reveals a transcriptional immune response in the breast-fed infant gut associated with diet-specific microbiota
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Genome Biology 2012, 13:243Plant genome sequencing
Michael Schatz and colleagues assess challenges in de novo plant genome assembly and review the best practices for the plant community
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Genome Biology 2012, 13:153Arabidopsis circadian clock
David Somers highlights three recent papers that arrive at a surprising conclusion about how TOC1 functions in the plant circadian clock
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Genome Biology 2012, 13:R31Rat model genomes
The genome and transcriptome sequences of the founder strains of the HXB/BXH panel of recombinant inbred rat strains
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Genome Biology 2012, 13:R30Bacterial mRNA decay
RNA-seq is used to determine mRNA decay rates to single nucleotide resolution in the Gram positive bacterium Bacillus cereus
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Genome Biology 2012, 13:R29RedeR
A method for visualizing complex, large-scale networks that combines R/Bioconductor with Java, and allows the incorporation of plug-ins
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Featured free review
From RNA-seq reads to differential expression results
Many methods and tools are available for preprocessing high-throughput RNA sequencing data and detecting differential expression.
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Latest issue
The complete issue of Genome Biology Volume 13 Issue 4 is now available.
2012 special issue Epigenomics
Following on from our highly successful special issue on exome sequencing in 2011, we are now inviting submissions to the 2012 special issue which will focus on epigenomics.
For more information, see here.
Beyond the Genome 2012
The 3rd annual Beyond the Genome conference takes place in Harvard Medical School, Boston from 27-29 September 2012.
Keynote speakers announced:
Richard Gibbs, Baylor College of Medicine, USA
Stuart Schreiber, Broad Institute of Harvard and MIT, USA
Genome Biology podcast
To coincide with September's special issue, we talk with Jim Lupski, Jay Shendure, Elaine Mardis and Joris Veltman about the challenges of identifying disease genes using exome sequencing and whole genome sequencing.
Download MP3 file (Size: 35.8MB)
Twitter updates
- Theme from last 2 talks: small effective human pop size due to bottlenecks has resulted in higher prevalence of deleterious mutations #bog12 3:21 PM May 12th, 2012
- Jeff Kidd: strong bottleneck apparent in all Out Of Africa pops, estimated to have occurred 40kya. San-specific bottleneck 50kya #bog12 3:15 PM May 12th, 2012
- JN: SIFT + 2 other methods predicted signif # of the SNPs to be deleterious #bog12 We recently published SIFT Indel http://t.co/EZ70P18v 3:05 PM May 12th, 2012
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