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Current Opinion in Drug Discovery & Development

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Current Opinion in Drug Discovery & Development, Volume 12, Issue 4 (July 2009)        [more info]

 
Current Opinion in Drug Discovery & Development is a bimonthly review journal that has established itself as a unique journal encompassing all chemical aspects of drug R&D, from the initial concept stage, through to process development.

Access to the full text or PDF of articles from Current Opinion in Drug Discovery & Development requires a subscription to the journal. Individual PDFs may be purchased by contacting ts.ids@thomson.com.


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Paper alert
P Norman, DP Rotella, B Sherborne
Current Opinion in Drug Discovery and Development 2009, 12:421-434 (24June2009)
[Abstract] [Full text] [PDF]


Patent alert
Reuters Current Awareness Analysts Thomson
Current Opinion in Drug Discovery and Development 2009, 12:435-439 (24June2009)
[Abstract] [Full text] [PDF]


Web alert
MA Stidham
Current Opinion in Drug Discovery and Development 2009, 12:440-442 (24June2009)
[Abstract] [Full text] [PDF]


Personalized medicine - A paradigm for a sustainable pharmaceutical industry?
S Chackalamannil, MC Desai
Current Opinion in Drug Discovery and Development 2009, 12:443-445 (24June2009)
[Abstract] [Full text] [PDF]


Recent progress in the discovery and development of negative allosteric modulators of mGluR5
CW Lindsley, KA Emmitte
Current Opinion in Drug Discovery and Development 2009, 12:446-457 (24June2009)
[Abstract] [Full text] [PDF]


PDE10A inhibitors: An assessment of the current CNS drug discovery landscape
T Chappie, J Humphrey, F Menniti, C Schmidt
Current Opinion in Drug Discovery and Development 2009, 12:458-467 (24June2009)
[Abstract] [Full text] [PDF]


Glycine transport inhibitors for the treatment of schizophrenia: Symptom and disease modification
DC Javitt
Current Opinion in Drug Discovery and Development 2009, 12:468-478 (24June2009)
[Abstract] [Full text] [PDF]


Prospects for the development of fusion inhibitors to treat human respiratory syncytial virus infection
JD Bonfanti, D Roymans
Current Opinion in Drug Discovery and Development 2009, 12:479-487 (24June2009)
[Abstract] [Full text] [PDF]


The importance of drug-target residence time
R Zhang, F Monsma
Current Opinion in Drug Discovery and Development 2009, 12:488-496 (24June2009)
[Abstract] [Full text] [PDF]


Direct Factor Xa and direct thrombin inhibitors: A clinical trial update
AGG Turpie
Current Opinion in Drug Discovery and Development 2009, 12:497-508 (24June2009)
[Abstract] [Full text] [PDF]


Physiologically based pharmacokinetic (PBPK) modeling and simulation: Applications in lead optimization
SA Peters, AL Ungell, H Dolgos
Current Opinion in Drug Discovery and Development 2009, 12:509-518 (24June2009)
[Abstract] [Full text] [PDF]


GPR119 agonists: A promising new approach for the treatment of type 2 diabetes and related metabolic disorders
U Shah
Current Opinion in Drug Discovery and Development 2009, 12:519-532 (24June2009)
[Abstract] [Full text] [PDF]


Is there a future for Aurora kinase inhibitors for anticancer therapy?
P Carpinelli, J Moll
Current Opinion in Drug Discovery and Development 2009, 12:533-542 (24June2009)
[Abstract] [Full text] [PDF]


Small molecules targeting sodium and calcium channels for neuropathic pain
B Bear, J Asgian, A Termin, N Zimmermann
Current Opinion in Drug Discovery and Development 2009, 12:543-561 (24June2009)
[Abstract] [Full text] [PDF]


Erratum [Fungal biotransformations of cannabinoids: Potential for new effective drugs. CODDD (2009) 12(2):305-312. Correction: the structure of chrysanthenol that appears in Figures 3 and 4]
Current Opinion in Drug Discovery and Development 2009, 12:562 (24June2009)
[Abstract] [Full text] [PDF]

 

 

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