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Current Opinion in Drug Discovery & Development, Volume 12, Issue 5 (September 2009)        [more info]

 
Current Opinion in Drug Discovery & Development is a bimonthly review journal that has established itself as a unique journal encompassing all chemical aspects of drug R&D, from the initial concept stage, through to process development.

Access to the full text or PDF of articles from Current Opinion in Drug Discovery & Development requires a subscription to the journal. Individual PDFs may be purchased by contacting ts.ids@thomson.com.


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Paper alert
P Norman, B Sherbone
Current Opinion in Drug Discovery & Development 2009, 12:563-573 (4September2009)
 [Abstract] [Full text] [PDF]


Patent alert
Analysts Thomson Reuters Current Awareness
Current Opinion in Drug Discovery & Development 2009, 12:574-578 (4September2009)
 [Abstract] [Full text] [PDF]


Web alert
MA Stidham
Current Opinion in Drug Discovery & Development 2009, 12:579-580 (4September2009)
 [Abstract] [Full text] [PDF]


The importance of target validation in drug discovery and development
JA Lowe, P Jones, DM Wilson
Current Opinion in Drug Discovery & Development 2009, 12:581-584 (4September2009)
 [Abstract] [Full text] [PDF]


Direct small-molecule kinase activation: Novel approaches for a new era of drug discovery
GL Simpson, JA Hughes, Y Washio, SM Bertrand
Current Opinion in Drug Discovery & Development 2009, 12:585-596 (4September2009)
 [Abstract] [Full text] [PDF]


The molecular machinery of mitochondrial fusion and fission: An opportunity for drug discovery?
A Zorzano, D Sebastin, J Segals, M Palacn
Current Opinion in Drug Discovery & Development 2009, 12:597-606 (4September2009)
 [Abstract] [Full text] [PDF]


The future therapeutic potential of histone demethylases: A critical analysis
G Natoli, G Testa, F De Santa
Current Opinion in Drug Discovery & Development 2009, 12:607-615 (4September2009)
 [Abstract] [Full text] [PDF]


Protein arginine deiminase 4 (PAD4): Current understanding and future therapeutic potential
JE Jones, CP Causey, B Knuckley, JL Slack-Noyes, PR Thompson
Current Opinion in Drug Discovery & Development 2009, 12:616-627 (4September2009)
 [Abstract] [Full text] [PDF]


A new generation of anti-histamines: Histamine H4 receptor antagonists on their way to the clinic
H Engelhardt, RA Smits, R Leurs, E Haaksma, IJP de Esch
Current Opinion in Drug Discovery & Development 2009, 12:628-643 (4September2009)
 [Abstract] [Full text] [PDF]


Resolvins: Current understanding and future potential in the control of inflammation
GL Bannenberg
Current Opinion in Drug Discovery & Development 2009, 12:644-658 (4September2009)
 [Abstract] [Full text] [PDF]


The role of human bromodomains in chromatin biology and gene transcription
R Sanchez, M Zhou
Current Opinion in Drug Discovery & Development 2009, 12:659-665 (4September2009)
 [Abstract] [Full text] [PDF]


Small-molecule modulation of cellular chaperones to treat protein misfolding disorders
LA Sloan, MC Fillmore, I Churcher
Current Opinion in Drug Discovery & Development 2009, 12:666-681 (4September2009)
 [Abstract] [Full text] [PDF]


Future potential and status of selective sodium channel blockers for the treatment of pain
BT Priest
Current Opinion in Drug Discovery & Development 2009, 12:682-692 (4September2009)
 [Abstract] [Full text] [PDF]


Acid-sensing ion channels: A new target for pain and CNS diseases
KA Sluka, OC Winter, JA Wemmie
Current Opinion in Drug Discovery & Development 2009, 12:693-704 (4September2009)
 [Abstract] [Full text] [PDF]


Erratum: Small molecules targeting sodium and calcium channels for neuropathic pain. Current Opinion in Drug Discovery & Development (2009) 12(4):543-561
Current Opinion in Drug Discovery & Development 2009, 12:705 (4September2009)
 [Abstract] [Full text] [PDF]

 

 

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